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Service Security of Underwater Tunnel Lining Structures and Corresponding Guarantee Countermeasures

He Chuan,Liu Sijin,Zhang Yuchun and Feng Kun

Strategic Study of CAE 2017, Volume 19, Issue 6,   Pages 44-51 doi: 10.15302/J-SSCAE-2017.06.007

Abstract: Based on these analyses, countermeasures guaranteeing the long-life security of underwater tunnel structuresThese countermeasures are being sought to effectively protect and ensure the service performance of theThese security measures can ensure the safe performance of the structure during its entire life cycleThis research can serve as a reference for enhancing the structural security of underwater tunnels and

Keywords： underwater tunnels     service security     security guarantee countermeasures     long life     structural defects    

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Analysis and countermeasures of natural gas development in China

Wenzhi ZHAO, Ailin JIA, Guosheng ZHANG

Frontiers of Engineering Management 2019, Volume 6, Issue 4,   Pages 477-484 doi: 10.1007/s42524-019-0064-x

Abstract: In this study, the future situation of China’s natural gas is forecasted, and relevant countermeasures

Keywords： natural gas     yield     consumption     external dependency     security situation    

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Wind Resistance Safety of Marine Bridge Engineering and Corresponding Guarantee Countermeasures

Liao Haili , Li Mingshui , Zhou Qian

Strategic Study of CAE 2019, Volume 21, Issue 3,   Pages 12-17 doi: 10.15302/J-SSCAE-2019.03.012

Abstract: technical problems regarding four aspects: wind field characteristics, wind-resistant design theories, countermeasuresBased on these analyses, countermeasures for guaranteeing wind resistance safety of marine bridges are

Keywords： marine bridge engineering     wind resistance safety     typhoon     aerodynamic countermeasures    

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Strategies and Countermeasures for Ensuring Energy Security in China

Huang Weihe, Han Jingkuan, Wang Yusheng, Shen Juexin, Cheng Lei

Strategic Study of CAE 2021, Volume 23, Issue 1,   Pages 112-117 doi: 10.15302/J-SSCAE-2021.01.017

Abstract:

Energy security is important for the security system of a country.Affected by global geopolitics and the COVID-19 pandemic, China’s energy security is currentlyThis study first reviews the evolution of the energy security concept and summarizes the energy securityThen the energy security in China is defined from five dimensions: sustainable development, guaranteedMoreover, the situation faced by China’s energy security is studied and corresponding strategies

Keywords： energy revolution     energy security     security assurance     energy economy     situation analysis    

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Reliability guarantee framework for the Sichuan–Tibet Railway

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 480-491 doi: 10.1007/s42524-021-0170-4

Abstract: Consequently, countermeasures are necessary and urgent to ensure its safety and reliability in the wholeThis study proposes a novel reliability framework to guarantee the ideal operation state of the Sichuan–Tibet

Keywords： Sichuan–Tibet Railway     operational efficiency     reliability guarantee     Nine-Connotation     implementation    

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Discussion on Long-Life Security Strategies for Railway Track Engineering

Wang Ping,Chen Rong and An Boyang

Strategic Study of CAE 2017, Volume 19, Issue 6,   Pages 66-71 doi: 10.15302/J-SSCAE-2017.06.010

Abstract: Therefore, it is particularly urgent to organize and implement a long-life security plan for railway

Keywords： railway track engineering     long life     safety guarantee     Shift2Rail    

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Energy Revolution and Security Guarantee of China’s Energy Economy

Huang Weihe, Mei Yingdan, Wu Lili, Liang Yunling, Zhao Xiaoli

Strategic Study of CAE 2021, Volume 23, Issue 1,   Pages 124-132 doi: 10.15302/J-SSCAE-2021.01.018

Abstract: We conclude that China’s energy revolution is less likely to affect the security of the energyTo better ensure the security of energy economy in the process of China’s energy revolution, we

Keywords： energy revolution     security of energy economy     energy structure     energy price     national economy    

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Implementation Countermeasures for Information Security Management of Intelligent Connected Vehicles

Zhao Shijia, Xu Ke, Xue Xiaoqing, Qiao Yingjun

Strategic Study of CAE 2019, Volume 21, Issue 3,   Pages 108-113 doi: 10.15302/J-SSCAE-2019.03.006

Abstract: Meanwhile, multiple risks are also brought to information security by intelligentization and networkingIn recent years, hacker attacks frequently occur, and information security not only affects driving safetyand user data safety, but also threatens national security when being damaged.So, information security issues have attracted great attention from governments all over the world.In this context, China should promote the development and management of the information security of the

Keywords： intelligent connected vehicles     information security     automotive industry     management    

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Countermeasures for Assuring Water Ecological Environment Security in China

Huo Shouliang,Zhang Hanxiao,Jin Xiaowei ,Cao Xiaofeng,Wu Fengchang

Strategic Study of CAE 2022, Volume 24, Issue 5,   Pages 1-7 doi: 10.15302/J-SSCAE-2022.05.001

Abstract: Furthermore, we proposed the following four countermeasures: (1) revising the Environmental Quality Standards

Keywords： water ecological environment     ecological civilization     quality improvement     water ecological security    

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AI-Enabled Cyberspace Attacks: Security Risks and Countermeasures

Fang Binxing, Shi Jinqiao, Wang Zhongru, Yu Weiqiang

Strategic Study of CAE 2021, Volume 23, Issue 3,   Pages 60-66 doi: 10.15302/J-SSCAE-2021.03.002

Abstract: Thus, studying the security problems induced by the deep fusion of AI and cyberspace security becomesIn this article, we systematically analyze the major national security issues induced by the fusion,These issues aggravate the existing security risks and trigger new threats.To effectively address the security threats of AI-enabled cyber attacks, we suggest that an intelligentSharing of AI security data assets should be encouraged to develop a data-centered path for AI-enabled

Keywords： artificial intelligence (AI)     cyber attack and defense     national security     autonomous collaboration    

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Technical Countermeasures for Security Risks of Artificial General Intelligence

Liu Yuqing, Zhang Yuhuai, Duan Peiqi, Shi Boxin, Yu Zhaofei, Huang Tiejun, Gao Wen

Strategic Study of CAE 2021, Volume 23, Issue 3,   Pages 75-81 doi: 10.15302/J-SSCAE-2021.03.005

Abstract:

Human beings might face significant security risks after entering intosummarizing the difference between AGI and traditional artificial intelligence, we analyze the sources of the securityMoreover, we propose a security risk assessment system for AGI from the aspects of ability, motivationSubsequently, we discuss the defense countermeasures in the research and application stages.

Keywords： artificial general intelligence (AGI)     security risk     risk assessment     coping strategy    

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CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 322-338 doi: 10.1007/s11684-021-0901-2

Abstract: Immune-based therapies have experienced a pronounced breakthrough in the past decades as they acquired multiple US Food and Drug Administration (FDA) approvals for various indications. To date, six chimeric antigen receptor T cell (CAR-T) therapies have been permitted for the treatment of certain patients with relapsed/refractory hematologic malignancies. However, several clinical trials of solid tumor CAR-T therapies were prematurely terminated, or they reported life-threatening treatment-related damages to healthy tissues. The simultaneous expression of target antigens by healthy organs and tumor cells is partly responsible for such toxicities. Alongside targeting tumor-specific antigens, targeting the aberrantly glycosylated glycoforms of tumor-associated antigens can also minimize the off-tumor effects of CAR-T therapies. Tn, T, and sialyl-Tn antigens have been reported to be involved in tumor progression and metastasis, and their expression results from the dysregulation of a series of glycosyltransferases and the endoplasmic reticulum protein chaperone, Cosmc. Moreover, these glycoforms have been associated with various types of cancers, including prostate, breast, colon, gastric, and lung cancers. Here, we discuss how underglycosylated antigens emerge and then detail the latest advances in the development of CAR-T-based immunotherapies that target some of such antigens.

Keywords： cancer immunotherapy     chimeric antigen receptor     solid tumors     tumor-associated antigen     glycosylation     O-glycans     adoptive cell therapy    

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Safety Guarantee Measures for Subsea Shield Tunnel Segments Based on Life Cycle Deterioration Analysis

Liu Sijin,He Chuan,Sun Qi and Feng Kun

Strategic Study of CAE 2017, Volume 19, Issue 6,   Pages 52-60 doi: 10.15302/J-SSCAE-2017.06.008

Abstract:

The segment joint is the weak link in the lining structure of subsea tunnels, as it is under the continuous coupled effect of high water pressure and the corrosive seawater environment. If its performance deteriorates, it will seriously affect the safety of the lining structure of entire subsea shield tunnels. Based on an analysis of existing research into segment joint erosion and deterioration, a tunnel service time factor is introduced. Considering the influence of seawater pressure infiltration and chloride ion erosion and migration, a model analyzing the erosion and deterioration of the segment joint over its whole life cycle was subsequently established. The law governing the progressive erosion and deterioration of the segment joints of subsea tunnels over the entire life cycle was analyzed. The effects of seawater pressure and ion concentration on the erosion, deterioration, and steel corrosion of segment joints were studied. Based on the analysis of erosion and deterioration over the entire life cycle, economic and rational measures to ensure the long-term safety of the segment lining structure of subsea shield tunnels were proposed.

Keywords： shield tunnel     safety guarantee     deterioration analysis     ion erosion     segment joint    

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Genetic Crop Improvement: A Guarantee for Sustainable Agricultural Production

Jianmin Wan

Engineering 2018, Volume 4, Issue 4,   Pages 431-432 doi: 10.1016/j.eng.2018.07.019

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Soil security and global food security

Frontiers of Agricultural Science and Engineering doi: 10.15302/J-FASE-2023530

Abstract:

● Much of the world’s agricultural land has been degraded through soil loss and degradation of soil organic matter.

Keywords： Agriculture     soil security     food security     regenerative    

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Title Author Date Type Operation

Service Security of Underwater Tunnel Lining Structures and Corresponding Guarantee Countermeasures

He Chuan,Liu Sijin,Zhang Yuchun and Feng Kun

Journal Article

Analysis and countermeasures of natural gas development in China

Wenzhi ZHAO, Ailin JIA, Guosheng ZHANG

Journal Article

Wind Resistance Safety of Marine Bridge Engineering and Corresponding Guarantee Countermeasures

Liao Haili , Li Mingshui , Zhou Qian

Journal Article

Strategies and Countermeasures for Ensuring Energy Security in China

Huang Weihe, Han Jingkuan, Wang Yusheng, Shen Juexin, Cheng Lei

Journal Article

Reliability guarantee framework for the Sichuan–Tibet Railway

Journal Article

Discussion on Long-Life Security Strategies for Railway Track Engineering

Wang Ping,Chen Rong and An Boyang

Journal Article

Energy Revolution and Security Guarantee of China’s Energy Economy

Huang Weihe, Mei Yingdan, Wu Lili, Liang Yunling, Zhao Xiaoli

Journal Article

Implementation Countermeasures for Information Security Management of Intelligent Connected Vehicles

Zhao Shijia, Xu Ke, Xue Xiaoqing, Qiao Yingjun

Journal Article

Countermeasures for Assuring Water Ecological Environment Security in China

Huo Shouliang,Zhang Hanxiao,Jin Xiaowei ,Cao Xiaofeng,Wu Fengchang

Journal Article

AI-Enabled Cyberspace Attacks: Security Risks and Countermeasures

Fang Binxing, Shi Jinqiao, Wang Zhongru, Yu Weiqiang

Journal Article

Technical Countermeasures for Security Risks of Artificial General Intelligence

Liu Yuqing, Zhang Yuhuai, Duan Peiqi, Shi Boxin, Yu Zhaofei, Huang Tiejun, Gao Wen

Journal Article

CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a

Journal Article

Safety Guarantee Measures for Subsea Shield Tunnel Segments Based on Life Cycle Deterioration Analysis

Liu Sijin,He Chuan,Sun Qi and Feng Kun

Journal Article

Genetic Crop Improvement: A Guarantee for Sustainable Agricultural Production

Jianmin Wan

Journal Article

Soil security and global food security

Journal Article